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Ragasa, Consolacion Y, Ph. D.: Home


Dr. Consolacion Y. Ragasa

Scope Note

     This webliography consists mostly of abstracts of selected papers and studies written by Dr. Consolacion Y. Ragasa. Some of the publications were written with other authors.

     A recipient of the Achievement Award in Chemical Research by the Philippine Federation of Chemistry Societies, Dr. Consolacion Y. Ragasa is a University fellow and a full-time professor of the Chemistry Department of De La Salle University-Manila.. Dr. Ragasa earned her Doctor of Philosophy in Chemistry, Master of Science in Chemistry and Bachelor of Science in Chemistry from the University of the Philippines. Her specialization includes chemistry, phytochemistry and natural products.


Internet Sites

An Antifungal Cadinanolide from Pseudoelephantopus spicatus
[Retrieved September 15, 2008]

"A new sesquiterpene lactone was obtained from the chloroform extract of Pseudoelephantopus spicatus. Its structure was elucidated by extensive one dimensional (1D) and 2D NMR spectroscopy and mass spectrometry. It was found to exhibit moderate antifungal activity against C. albicans and A. niger, and low activity against T. mentagrophytes, S. aureus, E. coli and P. aeruginosa. It was inactive against B. subtilis"

Diastereomeric Diterpenes from Coleus blumei
[Retrieved September 15, 2008]

"The chloroform extract of the air-dried leaves of Coleus blumei afforded a mixture of diastereomoers of a new abietane type diterpene whose structures were elucidated by extensive one and two dimensional (1D, 2D) NMR and mass spectrometry. Acetylation of the mixture afforded a single compound. Antimicrobial tests on the diterpene indicate that it is active against Bacillus subtilis, Pseudomonas aeruginosa and Candida albicans."

Isolation, Structure Elucidation, and Antimicrobial Assay of Secondary Metabolites From Five Philippine Medicinal Plants
[Retrieved September 26, 2008:]

"Presents the abstracts of five papers which resulted from studies on five medicinal plants."

New Furanoid Diterpenes from Caesalpinia pulcherrima
[Retrieved September 19, 2008]

"A new cassane-type diterpene isovouacapenol E (1) was isolated from the leaves of Caesalpinia pulcherrima, together with the known compounds caesaldekarin A (3), spathulenol (4), caryophyllene oxide (5), phytol, and sitosterol. The structure of 1 was elucidated by spectral data interpretation."

A Triterpene riterpene from Rosa sp.
[Retrieved September 22, 2008]

"This article is written with Agnes B. Alimboyoguen and John A. Rideout of the School of Chemical and Biomedical Sciences, Central Queensland University. It presents the dichloromethane extract of red rose petals which afforded 2-oxopomolic acid (1) and sitosterol by silica gel chromatography. The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy. Antimicrobial tests on 1 indicated that it is active against the fungi C. albicans and T. mentagrophytes. It was also found to be slightly active against the bacteria E. coli, P. aeruginosa, and S. aureus. It was inactive against B. subtilis and A. niger."

Wonder drugs in waiting: how plant chemistry becomes a springboard for developing cures to ailments
[Retrieved September 22, 2008]

"This article presents the author's work which involves the isolation and structural elucidation of pure compounds found in the dozen of plants she studied. This is a basic research which adds to the chemical literature and creates new knowledge on the field. The study can provide input for re-isolation of the compounds discovered for further bioassay to determine its potential biological activities."

A new rearranged dolabellane diterpene from the soft coral Clavularia inflata.
[Retrieved September 20, 2008]

"A new dolabellane type diterpene 1 has been isolated through its acetate 1a. The structure of 1a was elucidated by extensive 1D and 2D NMR spectroscopy and confirmed by mass spectrometry. The structure of 1 was deduced by comparison of its NMR spectral data with those of 1a, while its relative stereochemistry was deduced by NOESY. The absolute stereochemistry of C-7 was determined by analyses of 1 separately esterified with R and S O-mandelic acids ."

New Xenicanes from Xenia viridis;jsessionid=2ppmrf9l05cjg.alexandra
[Retrieved September 20, 2008]

"The dichloromethane extract of Xenia viridis afforded two new xenicane diterpenoids (3 and 4) by silica gel chromatography. The oxirane ring of 3 was found to be susceptible to a slow ring opening under acidic conditions to afford 5. Their structures were elucidated by extensive 1D." and 2D NMR spectroscopy."

Secondary Metabolites from Tectona Philippinensis
[Retrieved September 20, 2008]

"The air-dried leaves of Tectona philippinensis, an endemic and endangered Philippine medicinal plant, afforded 5-hydroxy-3,7,4'-trimethoxyflavone (1), 5,4'-dihydroxy-3,7-dimethoxyflavone (2), squalene (3), a mixture of lupeol (4a) and �-amyrin (4b), chlorophyllide a (5), and hydrocarbons. Antimicrobial tests on 1 and 2 indicated low antifungal activity against the fungi, Candida albicans and Trichophyton mentagrophytes. Compound 1 was also found to have low antibacterial activity against Escherichia coli and Pseudomonas aeruginosa."

Terpenoids and sterols from Malachra FasciataThe leaves of Lagerstroemia speciosa afforded
[Retrieved September 13, 2008]

"A new natural product, 31-norlargerenol acetate (4), along with known compounds 24-methylenecycloartanol acetate (1), its 31-nor analog (2), largerenol acetate (3), tinotufolins C (5) and D (6), lutein, phytol, sitosterol and sitosterol acetate. The structure of 4 was elucidated by 1D and 2D NMR and mass spectroscopy ."